Learn about psilocybin therapy

Whether you're a veteran, a clinician, a curious person, or someone who's tried everything else — this is where to start. We've organized everything we know by topic.

Browse by Topic

Where would you like to begin?

Neuroscience

How does psilocybin actually work?

The brain mechanisms behind the therapeutic effect — default mode network disruption, neuroplasticity, and what the imaging data shows.

Oregon Law

Is psilocybin therapy legal?

Oregon Measure 109 created the first regulated services framework in the US. Here's exactly what it permits — and what it doesn't.

Veterans & PTSD

What does the evidence say for PTSD?

The strongest clinical evidence for psilocybin therapy is in treatment-resistant PTSD. The MAPS Phase 3 data, explained clearly.

Access

How do I actually access treatment?

A step-by-step guide to finding a licensed facilitator in Oregon, what to expect, and what questions to ask before you book.

Safety & Responsibility

What we think you should know before you decide

Psilocybin-assisted therapy has a strong and growing evidence base. It also has real contraindications, real costs, and real risks when accessed outside a regulated setting.

Myco Brief does not advocate for illegal use of psilocybin. We cover the science, the law, and the human experience — accurately, without agenda.

Contraindications exist

Lithium, certain antipsychotics, and personal or family history of psychosis are important factors. Always disclose your full medication list to your facilitator.

✓

Set and setting matter enormously

The research consistently shows that the quality of the environment, the facilitator relationship, and the preparation work are as important as the pharmacology.

Unregulated access carries real risk

The therapeutic benefit documented in clinical trials is inseparable from the professional setting in which it occurs. Unguided use is not the same as guided therapy.

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Oregon's framework exists for a reason

Licensing, training requirements, and the supervision mandate exist to protect clients. Use them. Verify your facilitator's OHA license number before booking.

Ready to take the next step?

We're here to help you navigate this clearly